3LDI
Crystal structure of aprotinin in complex with sucrose octasulfate: unusual interactions and implication for heparin binding
Summary for 3LDI
Entry DOI | 10.2210/pdb3ldi/pdb |
Related | 3LDJ 3LDM |
Descriptor | Pancreatic trypsin inhibitor, SULFATE ION, MERCURY (II) ION, ... (5 entities in total) |
Functional Keywords | aprotinin, sucrose octasulfate, disulfide bond, protease inhibitor, secreted, serine protease inhibitor, hydrolase inhibitor |
Biological source | Bos taurus (Bovine) |
Cellular location | Secreted: P00974 |
Total number of polymer chains | 5 |
Total formula weight | 35554.11 |
Authors | Yang, I.S.,Kim, T.G.,Park, B.S.,Kim, K.H. (deposition date: 2010-01-13, release date: 2010-06-23, Last modification date: 2014-02-12) |
Primary citation | Yang, I.S.,Kim, T.G.,Park, B.S.,Cho, K.J.,Lee, J.-H.,Park, Y.,Kim, K.H. Crystal structures of aprotinin and its complex with sucrose octasulfate reveal multiple modes of interactions with implications for heparin binding Biochem.Biophys.Res.Commun., 397:429-435, 2010 Cited by PubMed: 20529698DOI: 10.1016/j.bbrc.2010.05.113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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