3LDJ
Crystal structure of aprotinin in complex with sucrose octasulfate: unusual interactions and implication for heparin binding
Summary for 3LDJ
Entry DOI | 10.2210/pdb3ldj/pdb |
Related | 3LDM |
Related PRD ID | PRD_900013 |
Descriptor | Pancreatic trypsin inhibitor, 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, ACETATE ION, ... (4 entities in total) |
Functional Keywords | aprotinin, sucrose octasulfate, disulfide bond, protease inhibitor, secreted, serine protease inhibitor, hydrolase inhibitor |
Biological source | Bos taurus (bovine,cow,domestic cattle,domestic cow) |
Cellular location | Secreted: P00974 |
Total number of polymer chains | 3 |
Total formula weight | 20624.55 |
Authors | Yang, I.S.,Kim, T.G.,Park, B.S.,Kim, K.H. (deposition date: 2010-01-13, release date: 2010-09-15, Last modification date: 2020-07-29) |
Primary citation | Yang, I.S.,Kim, T.G.,Park, B.S.,Cho, K.J.,Lee, J.H.,Park, Y.,Kim, K.H. Crystal structures of aprotinin and its complex with sucrose octasulfate reveal multiple modes of interactions with implications for heparin binding. Biochem.Biophys.Res.Commun., 2010 Cited by PubMed: 20529698DOI: 10.1016/j.bbrc.2010.05.113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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