3LAF

Structure of DCC, a netrin-1 receptor

Summary for 3LAF

Entry DOI	10.2210/pdb3laf/pdb
Descriptor	Deleted in Colorectal Cancer, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	netrin-1 receptor, immunoglobulin superfamily, horseshoe, apoptosis
Biological source	Rattus norvegicus (rat)
Cellular location	Membrane ; Single-pass type I membrane protein : Q63155
Total number of polymer chains	1
Total formula weight	46900.99
Authors	Chen, Q.,Liu, J.-H.,Wang, J.-H. (deposition date: 2010-01-06, release date: 2011-03-02, Last modification date: 2020-07-29)
Primary citation	Chen, Q.,Sun, X.,Zhou, X.H.,Liu, J.H.,Wu, J.,Zhang, Y.,Wang, J.H. N-terminal horseshoe conformation of DCC is functionally required for axon guidance and might be shared by other neural receptors. J.Cell.Sci., 126:186-195, 2013 Cited by PubMed: 23038776 DOI: 10.1242/jcs.111278 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation