3LAF

Structure of DCC, a netrin-1 receptor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Deleted in Colorectal Cancer	polymer	403	44132.7	1	UniProt (Q63155) Pfam (PF13895) Pfam (PF07679) In PDB	Rattus norvegicus (rat)	Deleted in colorectal carcinoma, isoform CRA_a
2	B, C	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G15407YE)
3	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
4	A	SULFATE ION	non-polymer		96.1	12	Chemie (SO4)
5		water	water		18.0	218	Chemie (HOH)

Sequence modifications

A: 1 - 383 (UniProt: Q63155)

PDB	External Database	Details
Asp -19	-	expression tag
Arg -18	-	expression tag
Trp -17	-	expression tag
Gly -16	-	expression tag
Ser -15	-	expression tag
Glu -14	-	expression tag
Leu -13	-	expression tag
Glu -12	-	expression tag
Ser -11	-	expression tag
Ser -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
Gly -3	-	expression tag
Gly -2	-	expression tag
Arg -1	-	expression tag
Arg 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	44132.7
Branched	Number of molecules	2
	Total formula weight	1173.1
Non-Polymers*	Number of molecules	14
	Total formula weight	1595.2
All*	Total formula weight	46901.0

*Water molecules are not included.