3L5J
Crystal structure of FnIII domains of human GP130 (Domains 4-6)
Summary for 3L5J
| Entry DOI | 10.2210/pdb3l5j/pdb |
| Related | 3L5H 3L5I |
| Descriptor | Interleukin-6 receptor subunit beta, 1,2-ETHANEDIOL, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | cytokine receptor, fibronectin type iii domain, immune system |
| Biological source | Homo sapiens (human) |
| Cellular location | Isoform 1: Cell membrane ; Single-pass type I membrane protein . Isoform 2: Secreted : P40189 |
| Total number of polymer chains | 2 |
| Total formula weight | 65547.66 |
| Authors | Kershaw, N.J.,Zhang, J.-G.,Garrett, T.P.J.,Czabotar, P.E. (deposition date: 2009-12-22, release date: 2010-05-12, Last modification date: 2017-11-01) |
| Primary citation | Xu, Y.,Kershaw, N.J.,Luo, C.S.,Soo, P.,Pocock, M.J.,Czabotar, P.E.,Hilton, D.J.,Nicola, N.A.,Garrett, T.P.,Zhang, J.G. Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes. J.Biol.Chem., 285:21214-21218, 2010 Cited by PubMed: 20489211DOI: 10.1074/jbc.C110.129502 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.042 Å) |
Structure validation
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