3L4Q
Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein
Summary for 3L4Q
Entry DOI | 10.2210/pdb3l4q/pdb |
Descriptor | Non-structural protein 1, Phosphatidylinositol 3-kinase regulatory subunit beta, GLYCEROL, ... (4 entities in total) |
Functional Keywords | pi3k, phosphoinositide-3-kinase, influenza virus, ns1, kinase, viral protein-protein binding complex, viral protein/protein binding |
Biological source | Influenza A virus More |
Cellular location | Host nucleus: P03496 |
Total number of polymer chains | 4 |
Total formula weight | 78363.00 |
Authors | Hale, B.G.,Kerry, P.S.,Jackson, D.,Precious, B.L.,Gray, A.,Killip, M.J.,Randall, R.E.,Russell, R.J. (deposition date: 2009-12-21, release date: 2010-02-02, Last modification date: 2023-11-01) |
Primary citation | Hale, B.G.,Kerry, P.S.,Jackson, D.,Precious, B.L.,Gray, A.,Killip, M.J.,Randall, R.E.,Russell, R.J. Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein Proc.Natl.Acad.Sci.USA, 107:1954-1959, 2010 Cited by PubMed: 20133840DOI: 10.1073/pnas.0910715107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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