3L02

Crystal structure of N-acetyl-L-ornithine transcarbamylase E92A mutant complexed with carbamyl phosphate and N-succinyl-L-norvaline

Replaces:  2G65

Summary for 3L02

• Entry DOI: 10.2210/pdb3l02/pdb
• Related: 2FG7 3KZC 3KZK 3KZM 3KZN 3KZO 3L04 3L05 3L06
• Descriptor: N-acetylornithine carbamoyltransferase, N-(3-CARBOXYPROPANOYL)-L-NORVALINE, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ... (5 entities in total)
• Functional Keywords: transcarbamylase, amino-acid biosynthesis, arginine biosynthesis, cytoplasm, transferase
• Biological source: Xanthomonas campestris pv. campestris
• Cellular location: Cytoplasm (Probable): Q8P8J2
• Total number of polymer chains: 1
• Total formula weight: 40625.90

Authors

Shi, D.,Yu, X.,Allewell, N.M.,Tuchman, M. (deposition date: 2009-12-09, release date: 2010-03-31, Last modification date: 2023-11-22)

• Primary citation: Shi, D.,Yu, X.,Cabrera-Luque, J.,Chen, T.Y.,Roth, L.,Morizono, H.,Allewell, N.M.,Tuchman, M.; A single mutation in the active site swaps the substrate specificity of N-acetyl-L-ornithine transcarbamylase and N-succinyl-L-ornithine transcarbamylase.; Protein Sci., 16:1689-1699, 2007; PubMed: 17600144; DOI: 10.1110/ps.072919907

Experimental method

X-RAY DIFFRACTION (2.3 Å)