3KWV

Structural basis for the unfolding of anthrax lethal factor by protective antigen oligomers

3KWV の概要

• エントリーDOI: 10.2210/pdb3kwv/pdb
• 分子名称: Protective antigen PA-63, Lethal factor, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: bacillus anthracis, protective antigen, lethal factor, lethal toxin, octamer, protein transport, toxin, protein unfolding, protein translocation, cleavage on pair of basic residues, metal-binding, secreted, virulence, hydrolase, metalloprotease, protease, toxin-protein transport complex, toxin/protein transport
• 由来する生物種: Bacillus anthracis; 詳細
• 細胞内の位置: Secreted, extracellular space: P13423; Secreted: P15917
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 307350.72

構造登録者

Feld, G.K.,Kintzer, A.F.,Krantz, B.A. (登録日: 2009-12-01, 公開日: 2010-11-10, 最終更新日: 2023-09-06)

• 主引用文献: Feld, G.K.,Thoren, K.L.,Kintzer, A.F.,Sterling, H.J.,Tang, I.I.,Greenberg, S.G.,Williams, E.R.,Krantz, B.A.; Structural basis for the unfolding of anthrax lethal factor by protective antigen oligomers.; Nat.Struct.Mol.Biol., 17:1383-1390, 2010; PubMed: 21037566; DOI: 10.1038/nsmb.1923

実験手法

X-RAY DIFFRACTION (3.101 Å)