3KUY
DNA Stretching in the Nucleosome Facilitates Alkylation by an Intercalating Antitumor Agent
Summary for 3KUY
Entry DOI | 10.2210/pdb3kuy/pdb |
Related | 2NZD |
Descriptor | Histone H3.2, Histone H4, Histone H2A, ... (8 entities in total) |
Functional Keywords | nucleosome, chromatin, dna stretching, intercalation, alkylation, chromosomal protein, dna-binding, methylation, nucleosome core, nucleus, structural protein-dna complex, structural protein/dna |
Biological source | Xenopus laevis (African clawed frog) More |
Cellular location | Nucleus: Q6AZJ8 Q92130 Nucleus (By similarity): 3KUY 3KUY |
Total number of polymer chains | 10 |
Total formula weight | 196764.46 |
Authors | Wu, B.,Davey, C.A. (deposition date: 2009-11-28, release date: 2010-01-05, Last modification date: 2023-11-01) |
Primary citation | Davey, G.E.,Wu, B.,Dong, Y.,Surana, U.,Davey, C.A. DNA stretching in the nucleosome facilitates alkylation by an intercalating antitumour agent Nucleic Acids Res., 38:2081-2088, 2010 Cited by PubMed: 20026584DOI: 10.1093/nar/gkp1174 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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