Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3KUY

DNA Stretching in the Nucleosome Facilitates Alkylation by an Intercalating Antitumor Agent

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, EHistone H3.2polymer13515303.92UniProt (P84233)
Pfam (PF00125)
In PDB
Xenopus laevis (African clawed frog)
2B, FHistone H4polymer10211263.22UniProt (P62799)
Pfam (PF15511)
In PDB
Xenopus laevis (African clawed frog)
3C, GHistone H2Apolymer11912941.12UniProt (Q6AZJ8)
Pfam (PF00125)
Pfam (PF16211)
UniProt (by SIFTS) (P06897)
In PDB
Xenopus laevis (African clawed frog)
4D, HHistone H2Bpolymer12513848.12UniProt (Q92130)
Pfam (PF00125)
UniProt (by SIFTS) (P02281)
In PDB
Xenopus laevis (African clawed frog)
5IDNA (145-MER)polymer14544749.71
6JDNA (145-MER)polymer14544740.61
7EMANGANESE (II) IONnon-polymer54.91Chemie (MN)
8I, J2-[(2R)-oxiran-2-ylmethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dionenon-polymer253.32Chemie (ATV)
Sequence modifications
A, E: 1 - 135 (UniProt: P84233)
PDBExternal DatabaseDetails
Ala 102Gly 103SEE REMARK 999
D, H: -2 - 122 (UniProt: Q92130)
PDBExternal DatabaseDetails
Glu -1Asp 3SEE REMARK 999
Pro 7Ala 11SEE REMARK 999
Thr 29Ser 33SEE REMARK 999
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight196203.0
Non-Polymers*Number of molecules3
Total formula weight561.4
All*Total formula weight196764.5
*Water molecules are not included.

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon