3KSL

Structure of FPT bound to DATFP-DH-GPP

3KSL の概要

• エントリーDOI: 10.2210/pdb3ksl/pdb
• 分子名称: Farnesyltransferase, CAAX box, alpha, Protein farnesyltransferase subunit beta, MAGNESIUM ION, ... (6 entities in total)
• 機能のキーワード: transferase, prenyltransferase, metal-binding, phosphoprotein, zinc
• 由来する生物種: Rattus norvegicus (brown rat,rat,rats); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 93370.37

構造登録者

Hovlid, M.L.,Edelstein, R.L.,Henry, O.,Ochocki, J.,DeGraw, A.,Lenevich, S.,Talbot, T.,Young, V.,Hruza, A.W.,Lopez-Gallego, F.,Labello, N.P.,Strickland, C.L.,Schmidt-Dannert, C.,Distefano, M.D. (登録日: 2009-11-23, 公開日: 2009-12-22, 最終更新日: 2023-09-06)

• 主引用文献: Hovlid, M.L.,Edelstein, R.L.,Henry, O.,Ochocki, J.,DeGraw, A.,Lenevich, S.,Talbot, T.,Young, V.G.,Hruza, A.W.,Lopez-Gallego, F.,Labello, N.P.,Strickland, C.L.,Schmidt-Dannert, C.,Distefano, M.D.; Synthesis, properties, and applications of diazotrifluropropanoyl-containing photoactive analogs of farnesyl diphosphate containing modified linkages for enhanced stability.; Chem.Biol.Drug Des., 75:51-67, 2010; PubMed: 19954434; DOI: 10.1111/j.1747-0285.2009.00914.x

実験手法

X-RAY DIFFRACTION (2.05 Å)