3KK2
HIV-1 reverse transcriptase-DNA complex with dATP bound in the nucleotide binding site
Summary for 3KK2
Entry DOI | 10.2210/pdb3kk2/pdb |
Related | 3kjv 3kk1 3kk3 |
Descriptor | Reverse transcriptase p66 subunit, Reverse transcriptase p51 subunit, 5'-D(*AP*CP*A*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*(DOC))-3', ... (8 entities in total) |
Functional Keywords | hiv, reverse transcriptase, protein-dna complex, transferase-dna complex, transferase/dna |
Biological source | Human immunodeficiency virus type 1 (HIV-1) More |
Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P04585 P04585 |
Total number of polymer chains | 4 |
Total formula weight | 132881.80 |
Authors | Lansdon, E.B. (deposition date: 2009-11-04, release date: 2010-03-23, Last modification date: 2023-09-06) |
Primary citation | Lansdon, E.B.,Samuel, D.,Lagpacan, L.,Brendza, K.M.,White, K.L.,Hung, M.,Liu, X.,Boojamra, C.G.,Mackman, R.L.,Cihlar, T.,Ray, A.S.,McGrath, M.E.,Swaminathan, S. Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex. J.Mol.Biol., 397:967-978, 2010 Cited by PubMed: 20156454DOI: 10.1016/j.jmb.2010.02.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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