3KJ4

Structure of rat Nogo receptor bound to 1D9 antagonist antibody

3KJ4 の概要

• エントリーDOI: 10.2210/pdb3kj4/pdb
• 関連するPDBエントリー: 1OZN 1P8T
• 分子名称: Fab fragment 1D9 light chain, Fab fragment 1D9 heavy chain, Reticulon-4 receptor, ... (7 entities in total)
• 機能のキーワード: nogo receptor antagonist antibody, lrr, cell membrane, disulfide bond, glycoprotein, gpi-anchor, leucine-rich repeat, lipoprotein, membrane, receptor, immune system
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Cell membrane; Lipid-anchor, GPI-anchor (By similarity): Q99M75
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 160753.83

構造登録者

Silvian, L.F. (登録日: 2009-11-02, 公開日: 2010-09-22, 最終更新日: 2023-09-06)

• 主引用文献: Weinreb, P.H.,Wen, D.,Qian, F.,Wildes, C.P.,Garber, E.A.,Walus, L.,Jung, M.Y.,Wang, J.,Relton, J.K.,Amatucci, J.,Wang, R.,Porreca, F.,Silvian, L.,Meier, W.,Pepinsky, R.B.,Lee, D.H.; Resolution of disulfide heterogeneity in Nogo receptor 1 fusion proteins by molecular engineering.; Biotechnol Appl Biochem, 57:31-45, 2010; PubMed: 20815818; DOI: 10.1042/BA20100061

実験手法

X-RAY DIFFRACTION (3.1 Å)