3KJ4

Structure of rat Nogo receptor bound to 1D9 antagonist antibody

Summary for 3KJ4

• Entry DOI: 10.2210/pdb3kj4/pdb
• Related: 1OZN 1P8T
• Descriptor: Fab fragment 1D9 light chain, Fab fragment 1D9 heavy chain, Reticulon-4 receptor, ... (7 entities in total)
• Functional Keywords: nogo receptor antagonist antibody, lrr, cell membrane, disulfide bond, glycoprotein, gpi-anchor, leucine-rich repeat, lipoprotein, membrane, receptor, immune system
• Biological source: Mus musculus (mouse); More
• Cellular location: Cell membrane; Lipid-anchor, GPI-anchor (By similarity): Q99M75
• Total number of polymer chains: 6
• Total formula weight: 160753.83

Authors

Silvian, L.F. (deposition date: 2009-11-02, release date: 2010-09-22, Last modification date: 2023-09-06)

• Primary citation: Weinreb, P.H.,Wen, D.,Qian, F.,Wildes, C.P.,Garber, E.A.,Walus, L.,Jung, M.Y.,Wang, J.,Relton, J.K.,Amatucci, J.,Wang, R.,Porreca, F.,Silvian, L.,Meier, W.,Pepinsky, R.B.,Lee, D.H.; Resolution of disulfide heterogeneity in Nogo receptor 1 fusion proteins by molecular engineering.; Biotechnol Appl Biochem, 57:31-45, 2010; PubMed: 20815818; DOI: 10.1042/BA20100061

Experimental method

X-RAY DIFFRACTION (3.1 Å)