3KGV
Crystal Structure of Human DNA-dependent Protein Kinase Catalytic Subunit (DNA-PKcs)
Summary for 3KGV
Entry DOI | 10.2210/pdb3kgv/pdb |
EMDB information | 1102 1208 1209 1210 1270 1271 |
Descriptor | DNA-dependent Protein Kinase Catalytic Subunit (1 entity in total) |
Functional Keywords | dna-dependent protein kinase catalytic subunit, dna-pkcs, ku80, non-homologues end joining, dna repair, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 14 |
Total formula weight | 4918806.82 |
Authors | Sibanda, B.L.,Chirgadze, D.Y.,Blundell, T.L. (deposition date: 2009-10-29, release date: 2009-12-22, Last modification date: 2024-03-20) |
Primary citation | Sibanda, B.L.,Chirgadze, D.Y.,Blundell, T.L. Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats. Nature, 463:118-121, 2010 Cited by PubMed: 20023628DOI: 10.1038/nature08648 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (6.6 Å) |
Structure validation
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