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3KGS

V30M mutant human transthyretin (TTR) (apoV30M) pH 7.5

Summary for 3KGS
Entry DOI10.2210/pdb3kgs/pdb
Related3KGT 3KGU
DescriptorTransthyretin (2 entities in total)
Functional Keywordstransport protein, ttr, transthyretin, amyloid, amyloidosis, hormone, neuropathy, polymorphism, secreted, thyroid hormone, transport
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P02766
Total number of polymer chains2
Total formula weight27618.85
Authors
Trivella, D.B.,Polikarpov, I. (deposition date: 2009-10-29, release date: 2010-03-23, Last modification date: 2023-09-06)
Primary citationTrivella, D.B.,Bleicher, L.,Palmieri, L.C.,Wiggers, H.J.,Montanari, C.A.,Kelly, J.W.,Lima, L.M.,Foguel, D.,Polikarpov, I.
Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding.
J.Struct.Biol., 170:522-531, 2010
Cited by
PubMed: 20211733
DOI: 10.1016/j.jsb.2010.03.002
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

217705

건을2024-03-27부터공개중

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