3KFL

Leishmania major methionyl-tRNA synthetase in complex with methionyladenylate and pyrophosphate

3KFL の概要

• エントリーDOI: 10.2210/pdb3kfl/pdb
• 分子名称: Methionyl-tRNA synthetase, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] (2S)-2-azanyl-4-methylsulfanyl-butanoate, PYROPHOSPHATE 2-, ... (8 entities in total)
• 機能のキーワード: leishmania, parasite, aminoacyl-trna synthetase, trna ligase, aars, metrs, methionine, translation, atp-binding, nucleotide-binding, structural genomics, msgpp, ligase, medical structural genomics of pathogenic protozoa
• 由来する生物種: Leishmania major
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 65347.46

構造登録者

Larson, E.T.,Merritt, E.A.,Medical Structural Genomics of Pathogenic Protozoa (MSGPP) (登録日: 2009-10-27, 公開日: 2010-10-27, 最終更新日: 2023-09-06)

• 主引用文献: Larson, E.T.,Kim, J.E.,Zucker, F.H.,Kelley, A.,Mueller, N.,Napuli, A.J.,Verlinde, C.L.,Fan, E.,Buckner, F.S.,Van Voorhis, W.C.,Merritt, E.A.,Hol, W.G.; Structure of Leishmania major methionyl-tRNA synthetase in complex with intermediate products methionyladenylate and pyrophosphate.; Biochimie, 93:570-582, 2011; PubMed: 21144880; DOI: 10.1016/j.biochi.2010.11.015

実験手法

X-RAY DIFFRACTION (2 Å)