3K4S

The structure of the catalytic domain of human PDE4d with 4-(3-Butoxy-4-methoxyphenyl)methyl-2-imidazolidone

Summary for 3K4S

• Entry DOI: 10.2210/pdb3k4s/pdb
• Related: 3IAK
• Descriptor: cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, (4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one, ... (5 entities in total)
• Functional Keywords: nucleotide binding, phosphodiesterase, alternative splicing, camp, cytoplasm, cytoskeleton, hydrolase, membrane, metal-binding, phosphoprotein
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm (By similarity): Q08499
• Total number of polymer chains: 1
• Total formula weight: 40464.42

Authors

Crawley, L.,Cheng, R.K.Y.,Wood, M.,Barker, J.,Felicetti, B.,Whittaker, M. (deposition date: 2009-10-06, release date: 2009-10-20, Last modification date: 2023-09-06)

• Primary citation: Crawley, L.,Cheng, R.K.Y.,Wood, M.,Barker, J.,Felicetti, B.,Whittaker, M.; The structure of the catalytic domain of human PDE4d with 4-(3-Butoxy-4-methoxyphenyl)methyl-2-imidazolidone; To be Published,

Experimental method

X-RAY DIFFRACTION (2.05 Å)