3K26

Complex structure of EED and trimethylated H3K4

Summary for 3K26

• Entry DOI: 10.2210/pdb3k26/pdb
• Related: 3JPX 3JZG 3JZH 3JZN 3K27
• Descriptor: Polycomb protein EED, HISTONE PEPTIDE (3 entities in total)
• Functional Keywords: wd40, structural genomics, nppsfa, national project on protein structural and functional analysis, structural genomics consortium, sgc, alternative initiation, chromatin regulator, nucleus, phosphoprotein, repressor, transcription, transcription regulation, wd repeat, gene regulation, national project on protein structural and functional analyses
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: O75530
• Total number of polymer chains: 2
• Total formula weight: 43721.89

Authors

Bian, C.B.,Xu, C.,Qiu, W.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2009-09-29, release date: 2009-12-15, Last modification date: 2011-07-13)

• Primary citation: Xu, C.,Bian, C.,Yang, W.,Galka, M.,Ouyang, H.,Chen, C.,Qiu, W.,Liu, H.,Jones, A.E.,Mackenzie, F.,Pan, P.,Li, S.S.,Wang, H.,Min, J.; Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).; Proc.Natl.Acad.Sci.USA, 107:19266-19271, 2010; PubMed: 20974918; DOI: 10.1073/pnas.1008937107

Experimental method

X-RAY DIFFRACTION (1.58 Å)