3JV7

Structure of ADH-A from Rhodococcus ruber

Summary for 3JV7

Entry DOI	10.2210/pdb3jv7/pdb
Descriptor	ADH-A, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (6 entities in total)
Functional Keywords	dehydrogenase, nucleotide binding, rossmann-fold, oxidoreductase
Biological source	Rhodococcus ruber
Total number of polymer chains	4
Total formula weight	144774.33
Authors	Karabec, M.,Lyskowski, A.,Gruber, K. (deposition date: 2009-09-16, release date: 2010-08-25, Last modification date: 2023-11-01)
Primary citation	Karabec, M.,Lyskowski, A.,Tauber, K.C.,Steinkellner, G.,Kroutil, W.,Grogan, G.,Gruber, K. Structural insights into substrate specificity and solvent tolerance in alcohol dehydrogenase ADH-'A' from Rhodococcus ruber DSM 44541. Chem.Commun.(Camb.), 2010 Cited by PubMed Abstract: The structure of the alcohol dehydrogenase ADH-'A' from Rhodococcus ruber reveals possible reasons for its remarkable tolerance to organic co-solvents and suggests new directions for structure-informed mutagenesis to produce enzymes of altered substrate specificity or improved selectivity. PubMed: 20676439 DOI: 10.1039/c0cc00929f PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation