Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
A | 0008270 | molecular_function | zinc ion binding |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0046872 | molecular_function | metal ion binding |
B | 0000166 | molecular_function | nucleotide binding |
B | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
B | 0008270 | molecular_function | zinc ion binding |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0046872 | molecular_function | metal ion binding |
C | 0000166 | molecular_function | nucleotide binding |
C | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
C | 0008270 | molecular_function | zinc ion binding |
C | 0016491 | molecular_function | oxidoreductase activity |
C | 0046872 | molecular_function | metal ion binding |
D | 0000166 | molecular_function | nucleotide binding |
D | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
D | 0008270 | molecular_function | zinc ion binding |
D | 0016491 | molecular_function | oxidoreductase activity |
D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 501 |
Chain | Residue |
A | CYS92 |
A | CYS95 |
A | CYS98 |
A | CYS106 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ZN A 502 |
Chain | Residue |
A | CYS38 |
A | HIS62 |
A | ASP153 |
A | NAD503 |
A | ACY504 |
site_id | AC3 |
Number of Residues | 35 |
Details | BINDING SITE FOR RESIDUE NAD A 503 |
Chain | Residue |
A | HIS39 |
A | SER40 |
A | ASP153 |
A | THR157 |
A | VAL180 |
A | GLY181 |
A | GLY182 |
A | LEU183 |
A | ASP203 |
A | LEU204 |
A | ARG208 |
A | SER223 |
A | PHE246 |
A | VAL247 |
A | THR252 |
A | VAL269 |
A | GLY270 |
A | ILE271 |
A | PRO293 |
A | TYR294 |
A | TRP295 |
A | LEU332 |
A | ARG340 |
A | HOH346 |
A | HOH351 |
A | HOH368 |
A | HOH369 |
A | HOH371 |
A | HOH412 |
A | HOH414 |
A | HOH418 |
A | HOH422 |
A | ZN502 |
A | ACY504 |
D | PHE281 |
site_id | AC4 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE ACY A 504 |
Chain | Residue |
A | CYS38 |
A | SER40 |
A | HIS62 |
A | ASP153 |
A | TRP295 |
A | ZN502 |
A | NAD503 |
A | MPD505 |
site_id | AC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MPD A 505 |
Chain | Residue |
A | MET47 |
A | TYR54 |
A | TYR294 |
A | HOH347 |
A | ACY504 |
site_id | AC6 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN B 501 |
Chain | Residue |
B | CYS92 |
B | CYS95 |
B | CYS98 |
B | CYS106 |
site_id | AC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ZN B 502 |
Chain | Residue |
B | CYS38 |
B | HIS62 |
B | ASP153 |
B | NAD503 |
B | ACY504 |
site_id | AC8 |
Number of Residues | 33 |
Details | BINDING SITE FOR RESIDUE NAD B 503 |
Chain | Residue |
B | HIS39 |
B | SER40 |
B | ASP153 |
B | THR157 |
B | VAL180 |
B | GLY181 |
B | GLY182 |
B | LEU183 |
B | ASP203 |
B | LEU204 |
B | ARG208 |
B | SER223 |
B | PHE246 |
B | VAL247 |
B | THR252 |
B | VAL269 |
B | GLY270 |
B | ILE271 |
B | PRO293 |
B | TYR294 |
B | TRP295 |
B | ARG340 |
B | HOH346 |
B | HOH347 |
B | HOH376 |
B | HOH378 |
B | HOH380 |
B | HOH405 |
B | HOH438 |
B | ZN502 |
B | ACY504 |
B | HOH620 |
C | PHE281 |
site_id | AC9 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE ACY B 504 |
Chain | Residue |
B | CYS38 |
B | SER40 |
B | HIS62 |
B | ASP153 |
B | TRP295 |
B | ZN502 |
B | NAD503 |
B | MPD505 |
site_id | BC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MPD B 505 |
Chain | Residue |
B | MET47 |
B | TYR54 |
B | HOH469 |
B | ACY504 |
site_id | BC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ZN C 501 |
Chain | Residue |
C | CYS92 |
C | GLY93 |
C | CYS95 |
C | CYS98 |
C | CYS106 |
site_id | BC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ZN C 502 |
Chain | Residue |
C | CYS38 |
C | HIS62 |
C | ASP153 |
C | NAD503 |
C | ACY504 |
site_id | BC4 |
Number of Residues | 33 |
Details | BINDING SITE FOR RESIDUE NAD C 503 |
Chain | Residue |
B | PHE281 |
C | HIS39 |
C | SER40 |
C | ASP153 |
C | THR157 |
C | VAL180 |
C | GLY181 |
C | GLY182 |
C | LEU183 |
C | ASP203 |
C | LEU204 |
C | ARG208 |
C | SER223 |
C | PHE246 |
C | VAL247 |
C | THR252 |
C | VAL269 |
C | GLY270 |
C | ILE271 |
C | PRO293 |
C | TYR294 |
C | TRP295 |
C | LEU332 |
C | ARG340 |
C | HOH354 |
C | HOH359 |
C | HOH363 |
C | HOH364 |
C | HOH372 |
C | HOH377 |
C | ZN502 |
C | ACY504 |
C | HOH683 |
site_id | BC5 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE ACY C 504 |
Chain | Residue |
C | CYS38 |
C | SER40 |
C | HIS62 |
C | ASP153 |
C | TRP295 |
C | ZN502 |
C | NAD503 |
C | MPD505 |
site_id | BC6 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MPD C 505 |
Chain | Residue |
C | MET47 |
C | TYR54 |
C | ILE271 |
C | ACY504 |
site_id | BC7 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN D 501 |
Chain | Residue |
D | CYS92 |
D | CYS95 |
D | CYS98 |
D | CYS106 |
site_id | BC8 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ZN D 502 |
Chain | Residue |
D | CYS38 |
D | HIS62 |
D | ASP153 |
D | NAD503 |
D | ACY504 |
site_id | BC9 |
Number of Residues | 37 |
Details | BINDING SITE FOR RESIDUE NAD D 503 |
Chain | Residue |
A | PHE281 |
D | HIS39 |
D | SER40 |
D | ASP153 |
D | THR157 |
D | GLY179 |
D | VAL180 |
D | GLY181 |
D | GLY182 |
D | LEU183 |
D | ASP203 |
D | LEU204 |
D | ARG208 |
D | SER223 |
D | PHE246 |
D | VAL247 |
D | THR252 |
D | VAL269 |
D | GLY270 |
D | ILE271 |
D | PRO293 |
D | TYR294 |
D | TRP295 |
D | LEU332 |
D | ARG340 |
D | HOH354 |
D | HOH361 |
D | HOH384 |
D | HOH386 |
D | HOH416 |
D | HOH418 |
D | HOH421 |
D | HOH429 |
D | HOH439 |
D | HOH453 |
D | ZN502 |
D | ACY504 |
site_id | CC1 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE ACY D 504 |
Chain | Residue |
D | CYS38 |
D | SER40 |
D | HIS62 |
D | ASP153 |
D | TRP295 |
D | ZN502 |
D | NAD503 |
D | MPD505 |
site_id | CC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MPD D 505 |
Chain | Residue |
D | PHE43 |
D | TYR54 |
D | ILE271 |
D | HOH459 |
D | ACY504 |
Functional Information from PROSITE/UniProt
site_id | PS00059 |
Number of Residues | 15 |
Details | ADH_ZINC Zinc-containing alcohol dehydrogenases signature. GHEgVGTvaelGegV |
Chain | Residue | Details |
A | GLY61-VAL75 | |