3JTK

Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90055

3JTK の概要

• エントリーDOI: 10.2210/pdb3jtk/pdb
• 関連するPDBエントリー: 3IU1 3IU2 3IWE
• 分子名称: Glycylpeptide N-tetradecanoyltransferase 1, TETRADECANOYL-COA, (2R)-3-benzyl-2-(2-bromo-4-hydroxy-5-methoxyphenyl)-1,3-thiazolidin-4-one, ... (4 entities in total)
• 機能のキーワード: transferase, n-myristoyltransferase, nmt1, acyltransferase, phosphoprotein, structural genomics, structural genomics consortium, sgc
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P30419
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 91432.73

構造登録者

Qiu, W.,Hutchinson, A.,Wernimont, A.,Lin, Y.-H.,Kania, A.,Ravichandran, M.,Kozieradzki, I.,Cossar, D.,Schapira, M.,Arrowsmith, C.H.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Wyatt, P.G.,Ferguson, M.A.J.,Frearson, J.A.,Brand, S.Y.,Robinson, D.A.,Bochkarev, A.,Hui, R.,Structural Genomics Consortium (SGC) (登録日: 2009-09-12, 公開日: 2009-09-22, 最終更新日: 2023-09-06)

• 主引用文献: Qiu, W.,Hutchinson, A.,Wernimont, A.,Lin, Y.-H.,Kania, A.,Ravichandran, M.,Kozieradzki, I.,Cossar, D.,Schapira, M.,Arrowsmith, C.H.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Wyatt, P.G.,Ferguson, M.A.J.,Frearson, J.A.,Brand, S.Y.,Robinson, D.A.,Bochkarev, A.,Hui, R.; Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90055; To be Published,

実験手法

X-RAY DIFFRACTION (1.61 Å)