3JBL
Cryo-EM Structure of the Activated NAIP2/NLRC4 Inflammasome Reveals Nucleated Polymerization
Summary for 3JBL
Entry DOI | 10.2210/pdb3jbl/pdb |
EMDB information | 6458 6459 6460 |
Descriptor | NLR family CARD domain-containing protein 4 (1 entity in total) |
Functional Keywords | inflammasome, nlrc4, naip2, immune system |
Biological source | Mus musculus (mouse) |
Total number of polymer chains | 11 |
Total formula weight | 1168636.82 |
Authors | Zhang, L.,Chen, S.,Ruan, J.,Wu, J.,Tong, A.B.,Yin, Q.,Li, Y.,David, L.,Lu, A.,Wang, W.L.,Marks, C.,Ouyang, Q.,Zhang, X.,Mao, Y.,Wu, H. (deposition date: 2015-09-05, release date: 2015-10-21, Last modification date: 2018-07-18) |
Primary citation | Zhang, L.,Chen, S.,Ruan, J.,Wu, J.,Tong, A.B.,Yin, Q.,Li, Y.,David, L.,Lu, A.,Wang, W.L.,Marks, C.,Ouyang, Q.,Zhang, X.,Mao, Y.,Wu, H. Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization. Science, 350:404-409, 2015 Cited by PubMed: 26449474DOI: 10.1126/science.aac5789 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.5 Å) |
Structure validation
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