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3JBL

Cryo-EM Structure of the Activated NAIP2/NLRC4 Inflammasome Reveals Nucleated Polymerization

Summary for 3JBL
Entry DOI10.2210/pdb3jbl/pdb
EMDB information6458 6459 6460
DescriptorNLR family CARD domain-containing protein 4 (1 entity in total)
Functional Keywordsinflammasome, nlrc4, naip2, immune system
Biological sourceMus musculus (mouse)
Total number of polymer chains11
Total formula weight1168636.82
Authors
Zhang, L.,Chen, S.,Ruan, J.,Wu, J.,Tong, A.B.,Yin, Q.,Li, Y.,David, L.,Lu, A.,Wang, W.L.,Marks, C.,Ouyang, Q.,Zhang, X.,Mao, Y.,Wu, H. (deposition date: 2015-09-05, release date: 2015-10-21, Last modification date: 2018-07-18)
Primary citationZhang, L.,Chen, S.,Ruan, J.,Wu, J.,Tong, A.B.,Yin, Q.,Li, Y.,David, L.,Lu, A.,Wang, W.L.,Marks, C.,Ouyang, Q.,Zhang, X.,Mao, Y.,Wu, H.
Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.
Science, 350:404-409, 2015
Cited by
PubMed: 26449474
DOI: 10.1126/science.aac5789
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (4.5 Å)
Structure validation

217705

數據於2024-03-27公開中

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