3JAF

Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, glycine/ivermectin-bound state

3JAF の概要

関連するPDBエントリー3JAD 3JAE
EMDBエントリー6346 6344 6345
分子名称Glycine receptor subunit alphaZ1, N-ACETYL-D-GLUCOSAMINE, (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside (3 entities in total)
機能のキーワードcys loop receptor, alpha-1 glycine receptor, glycine, ivermectin, signaling protein
由来する生物種Danio rerio (zebra fish)
ポリマー鎖数5
分子量合計202705.24
構造登録者
Du, J.,Lu, W.,Wu, S.P.,Cheng, Y.F.,Gouaux, E. (登録日: 2015-06-08, 公開日: 2015-09-09, 最終更新日: 2018-07-18)
主引用文献
Du, J.,Lu, W.,Wu, S.,Cheng, Y.,Gouaux, E.
Glycine receptor mechanism elucidated by electron cryo-microscopy.
Nature, 526:224-229, 2015
PubMed: 26344198 (主引用文献が同じPDBエントリー)
DOI: 10.1038/nature14853
MImport into Mendeley
実験手法
ELECTRON MICROSCOPY (3.801 Å)
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構造検証レポート

ClashscoreRamachandran outliersSidechain outliers1900MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
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他の静止画像(非対称単位)

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