Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3IXG

X-ray crystal structure of the extended-spectrum AmpC T70I mutant beta-lactamase with and without benzo(b)thiophene-2-boronic acid bound at 2.14 Angstrom resolution

Summary for 3IXG
Entry DOI10.2210/pdb3ixg/pdb
Related3IWI 3IWO 3IWQ 3IXB 3IXD 3IXH
DescriptorBeta-lactamase, BENZO[B]THIOPHENE-2-BORONIC ACID (3 entities in total)
Functional Keywordsserine hydrolase, beta-lactamase, cephalosporinase, extended-spectrum antibiotic resistance, antibiotic resistance, hydrolase, periplasm
Biological sourceEscherichia coli
Cellular locationPeriplasm: P00811
Total number of polymer chains2
Total formula weight79377.97
Authors
Shoichet, B.K.,Thomas, V.L. (deposition date: 2009-09-04, release date: 2010-02-16, Last modification date: 2024-02-21)
Primary citationThomas, V.L.,McReynolds, A.C.,Shoichet, B.K.
Structural bases for stability-function tradeoffs in antibiotic resistance.
J.Mol.Biol., 396:47-59, 2010
Cited by
PubMed: 19913034
DOI: 10.1016/j.jmb.2009.11.005
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.14 Å)
Structure validation

217705

數據於2024-03-27公開中

PDB statisticsPDBj update infoContact PDBjnumon