3IXD

X-ray crystal structure of the extended-spectrum AmpC V298E mutant beta-lactamase at 2.64 Angstrom resolution

Summary for 3IXD

• Entry DOI: 10.2210/pdb3ixd/pdb
• Related: 3IWI 3IWO 3IWQ 3IXB 3IXG 3IXH
• Descriptor: Beta-lactamase, SULFATE ION (3 entities in total)
• Functional Keywords: serine hydrolase, beta-lactamase, cephalosporinase, extended-spectrum antibiotic resistance, antibiotic resistance, hydrolase, periplasm
• Biological source: Escherichia coli
• Cellular location: Periplasm: P00811
• Total number of polymer chains: 2
• Total formula weight: 79812.19

Authors

Shoichet, B.K.,Thomas, V.L. (deposition date: 2009-09-03, release date: 2010-02-16, Last modification date: 2024-02-21)

• Primary citation: Thomas, V.L.,McReynolds, A.C.,Shoichet, B.K.; Structural bases for stability-function tradeoffs in antibiotic resistance.; J.Mol.Biol., 396:47-59, 2010; PubMed: 19913034; DOI: 10.1016/j.jmb.2009.11.005

Experimental method

X-RAY DIFFRACTION (2.64 Å)