3IXG
X-ray crystal structure of the extended-spectrum AmpC T70I mutant beta-lactamase with and without benzo(b)thiophene-2-boronic acid bound at 2.14 Angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-lactamase | polymer | 358 | 39600.0 | 2 | UniProt (P00811) Pfam (PF00144) | Escherichia coli | Cephalosporinase |
| 2 | C (B) | BENZO[B]THIOPHENE-2-BORONIC ACID | non-polymer | 178.0 | 1 | Chemie (BZB) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 220 | Chemie (HOH) |
Sequence modifications
A, B: 4 - 361 (UniProt: P00811)
| PDB | External Database | Details |
|---|---|---|
| Ile 70 | Thr 86 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79200.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 178.0 | |
| All* | Total formula weight | 79378.0 |
