3IX9

Crystal structure of Streptococcus pneumoniae dihydrofolate reductase - Sp9 mutant

3IX9 の概要

• エントリーDOI: 10.2210/pdb3ix9/pdb
• 分子名称: Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, METHOTREXATE, ... (4 entities in total)
• 機能のキーワード: central beta sheet surrounded by 4 alpha helices, oxidoreductase
• 由来する生物種: Streptococcus pneumoniae
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 46860.24

構造登録者

Yennawar, N.H. (登録日: 2009-09-03, 公開日: 2010-02-02, 最終更新日: 2023-09-06)

• 主引用文献: Lee, J.,Yennawar, N.H.,Gam, J.,Benkovic, S.J.; Kinetic and structural characterization of dihydrofolate reductase from Streptococcus pneumoniae; Biochemistry, 49:195-206, 2010; PubMed: 19950924; DOI: 10.1021/bi901614m

実験手法

X-RAY DIFFRACTION (1.95 Å)