3ITK

Crystal structure of human UDP-glucose dehydrogenase Thr131Ala, apo form.

Summary for 3ITK

• Entry DOI: 10.2210/pdb3itk/pdb
• Related: 2Q3E 2QG4
• Descriptor: UDP-glucose 6-dehydrogenase, TETRAETHYLENE GLYCOL, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: oxidoreductase, structural genomics, structural genomics consortium, sgc, nad, phosphoprotein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 6
• Total formula weight: 314346.66

Authors

Chaikuad, A.,Egger, S.,Yue, W.W.,Sethi, R.,Filippakopoulos, P.,Muniz, J.R.C.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.M.,Kavanagh, K.L.,Nidetzky, B.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2009-08-28, release date: 2009-09-15, Last modification date: 2023-09-06)

• Primary citation: Egger, S.,Chaikuad, A.,Kavanagh, K.L.,Oppermann, U.,Nidetzky, B.; Structure and mechanism of human UDP-glucose 6-dehydrogenase.; J.Biol.Chem., 286:23877-23887, 2011; PubMed: 21502315; DOI: 10.1074/jbc.M111.234682

Experimental method

X-RAY DIFFRACTION (2.4 Å)