3ISQ

Crystal structure of human 4-Hydroxyphenylpyruvate dioxygenase

Summary for 3ISQ

• Entry DOI: 10.2210/pdb3isq/pdb
• Descriptor: 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: hydroxyphenylpyruvate, dioxygenase, tyrosine metabolism, disease mutation, iron, mental retardation, metal-binding, oxidoreductase, phenylalanine catabolism, phosphoprotein, tyrosine catabolism, structural genomics, structural genomics consortium, sgc
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 45399.90

Authors

Pilka, E.S.,Shafqat, N.,Cocking, R.,Bray, J.E.,Krojer, T.,Pike, A.C.W.,von Delft, F.,Yue, W.W.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Bountra, C.,Oppermann, U.,Kavanagh, K.L.,Structural Genomics Consortium (SGC) (deposition date: 2009-08-27, release date: 2009-09-15, Last modification date: 2023-11-01)

• Primary citation: Pilka, E.S.,Shafqat, N.,Cocking, R.,Bray, J.E.,Krojer, T.,Pike, A.C.W.,von Delft, F.,Yue, W.W.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Bountra, C.,Oppermann, U.,Kavanagh, K.L.; Crystal structure of human 4-Hydroxyphenylpyruvate dioxygenase; to be published,

Experimental method

X-RAY DIFFRACTION (1.75 Å)