3ISQ
Crystal structure of human 4-Hydroxyphenylpyruvate dioxygenase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 4-hydroxyphenylpyruvate dioxygenase | polymer | 393 | 45034.3 | 1 | UniProt (P32754) Pfam (PF00903) | Homo sapiens (human) | 4-hydroxyphenylpyruvic acid oxidase, HPPDase, 4HPPD, HPD |
| 2 | B (A) | COBALT (II) ION | non-polymer | 58.9 | 1 | Chemie (CO) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | E, F, G, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 6 | I (A) | water | water | 18.0 | 480 | Chemie (HOH) |
Sequence modifications
A: 8 - 393 (UniProt: P32754)
| PDB | External Database | Details |
|---|---|---|
| Ala 394 | - | expression tag |
| Glu 395 | - | expression tag |
| Asn 396 | - | expression tag |
| Leu 397 | - | expression tag |
| Tyr 398 | - | expression tag |
| Phe 399 | - | expression tag |
| Gln 400 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45034.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 365.6 | |
| All* | Total formula weight | 45399.9 |
