3INL

Human Mitochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, complexed with agonist Alda-1

Summary for 3INL

• Entry DOI: 10.2210/pdb3inl/pdb
• Related: 3INJ
• Descriptor: Aldehyde dehydrogenase, mitochondrial, SODIUM ION, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: oxidoreductase, aldh, e487k, rossmann fold, alda-1, activator, mitochondrion, nad, transit peptide
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion matrix: P05091
• Total number of polymer chains: 8
• Total formula weight: 440570.36

Authors

Perez-Miller, S.,Hurley, T.D. (deposition date: 2009-08-12, release date: 2010-01-12, Last modification date: 2024-02-21)

• Primary citation: Perez-Miller, S.,Younus, H.,Vanam, R.,Chen, C.H.,Mochly-Rosen, D.,Hurley, T.D.; Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant.; Nat.Struct.Mol.Biol., 17:159-164, 2010; PubMed: 20062057; DOI: 10.1038/nsmb.1737

Experimental method

X-RAY DIFFRACTION (1.862 Å)