3ILT
Crystal structure of the AMPA subunit GluR2 bound to the allosteric modulator, trichlormethiazide
Summary for 3ILT
Entry DOI | 10.2210/pdb3ilt/pdb |
Related | 3IJO 3IJX 3IK6 3IL1 3ILU |
Descriptor | Glutamate receptor 2, GLUTAMIC ACID, ZINC ION, ... (5 entities in total) |
Functional Keywords | glutamate receptor, glur2, ampa receptor, neurotransmitter receptor, s1s2, allosteric modulator, signaling protein |
Biological source | Rattus norvegicus (rat) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P19491 |
Total number of polymer chains | 3 |
Total formula weight | 88335.29 |
Authors | Ahmed, A.H.,Ptak, C.P.,Oswald, R.E. (deposition date: 2009-08-07, release date: 2009-09-15, Last modification date: 2023-09-06) |
Primary citation | Ptak, C.P.,Ahmed, A.H.,Oswald, R.E. Probing the allosteric modulator binding site of GluR2 with thiazide derivatives Biochemistry, 48:8594-8602, 2009 Cited by PubMed: 19673491DOI: 10.1021/bi901127s PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.107 Å) |
Structure validation
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