3II7
Crystal structure of the kelch domain of human KLHL7
Summary for 3II7
Entry DOI | 10.2210/pdb3ii7/pdb |
Descriptor | Kelch-like protein 7, 1,2-ETHANEDIOL (3 entities in total) |
Functional Keywords | protein-binding, kelch-repeat, structural genomics, structural genomics consortium, sgc, kelch repeat, nucleus, protein binding |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q8IXQ5 |
Total number of polymer chains | 1 |
Total formula weight | 35626.49 |
Authors | Chaikuad, A.,Thangaratnarajah, C.,Cooper, C.D.O.,Ugochukwu, E.,Muniz, J.R.C.,Krojer, T.,Sethi, R.,Pike, A.C.W.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Bullock, A.,Structural Genomics Consortium (SGC) (deposition date: 2009-07-31, release date: 2009-08-25, Last modification date: 2023-09-06) |
Primary citation | Canning, P.,Cooper, C.D.,Krojer, T.,Murray, J.W.,Pike, A.C.,Chaikuad, A.,Keates, T.,Thangaratnarajah, C.,Hojzan, V.,Ayinampudi, V.,Marsden, B.D.,Gileadi, O.,Knapp, S.,von Delft, F.,Bullock, A.N. Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases. J.Biol.Chem., 288:7803-7814, 2013 Cited by PubMed: 23349464DOI: 10.1074/jbc.M112.437996 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.63 Å) |
Structure validation
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