3I9G
Crystal structure of the LT1009 (SONEPCIZUMAB) antibody Fab fragment in complex with sphingosine-1-phosphate
Summary for 3I9G
Entry DOI | 10.2210/pdb3i9g/pdb |
Descriptor | Sonepcizumab antibody Fab fragment, heavy chain, Sonepcizumab antibody Fab fragment, light chain, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | antibody, fab, sphingosine-1-phosphate, calcium, immunoglobin, igg, immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 2 |
Total formula weight | 48051.25 |
Authors | Huxford, T. (deposition date: 2009-07-10, release date: 2009-09-29, Last modification date: 2011-07-13) |
Primary citation | Wojciak, J.M.,Zhu, N.,Schuerenberg, K.T.,Moreno, K.,Shestowsky, W.S.,Hiraiwa, M.,Sabbadini, R.,Huxford, T. The crystal structure of sphingosine-1-phosphate in complex with a Fab fragment reveals metal bridging of an antibody and its antigen. Proc.Natl.Acad.Sci.USA, 106:17717-17722, 2009 Cited by PubMed: 19815502DOI: 10.1073/pnas.0906153106 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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