3I93

Crystal structure of Mycobacterium tuberculosis dUTPase STOP138T mutant

Summary for 3I93

Entry DOI	10.2210/pdb3i93/pdb
Related	2PY4 3H6D 3HZA
Descriptor	Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, ... (5 entities in total)
Functional Keywords	jelly-roll, enzyme-ligand complex, hydrolase, magnesium, metal-binding, nucleotide metabolism
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	17304.63
Authors	Leveles, I.,Harmat, V.,Lopata, A.,Toth, J.,Vertessy, B.G. (deposition date: 2009-07-10, release date: 2009-11-24, Last modification date: 2023-09-06)
Primary citation	Takacs, E.,Nagy, G.,Leveles, I.,Harmat, V.,Lopata, A.,Toth, J.,Vertessy, B.G. Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases. Febs Lett., 584:3047-3054, 2010 Cited by PubMed: 20493855 DOI: 10.1016/j.febslet.2010.05.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation