3I8V

Crystal structure of human PDE4a with 4-(3-butoxy-4-methoxyphenyl)methyl-2-imidazolidone

Summary for 3I8V

• Entry DOI: 10.2210/pdb3i8v/pdb
• Descriptor: cAMP-specific 3',5'-cyclic phosphodiesterase 4A, ZINC ION, MAGNESIUM ION, ... (7 entities in total)
• Functional Keywords: cyclic-amp specific, camp, hydrolase, membrane, phosphoprotein
• Biological source: Homo sapiens (human)
• Cellular location: Isoform 1: Cytoplasm, perinuclear region. Isoform 2: Cytoplasm, perinuclear region. Isoform 4: Membrane; Peripheral membrane protein. Isoform 6: Cytoplasm, perinuclear region. Isoform 7: Cytoplasm: P27815
• Total number of polymer chains: 2
• Total formula weight: 82449.81

Authors

Cheng, R.K.Y.,Crawley, L.,Barker, J.,Wood, M.,Felicetti, B.,Whittaker, M. (deposition date: 2009-07-10, release date: 2009-07-21, Last modification date: 2023-11-22)

• Primary citation: Cheng, R.K.Y.,Crawley, L.,Barker, J.,Wood, M.,Felicetti, B.,Whittaker, M.; Crystal structure of human PDE4a with 4-(3-butoxy-4-methoxyphenyl)methyl-2-imidazolidone; To be Published,

Experimental method

X-RAY DIFFRACTION (2.25 Å)