3I8V
Crystal structure of human PDE4a with 4-(3-butoxy-4-methoxyphenyl)methyl-2-imidazolidone
Summary for 3I8V
Entry DOI | 10.2210/pdb3i8v/pdb |
Descriptor | cAMP-specific 3',5'-cyclic phosphodiesterase 4A, ZINC ION, MAGNESIUM ION, ... (7 entities in total) |
Functional Keywords | cyclic-amp specific, camp, hydrolase, membrane, phosphoprotein |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Cytoplasm, perinuclear region. Isoform 2: Cytoplasm, perinuclear region. Isoform 4: Membrane; Peripheral membrane protein. Isoform 6: Cytoplasm, perinuclear region. Isoform 7: Cytoplasm: P27815 |
Total number of polymer chains | 2 |
Total formula weight | 82449.81 |
Authors | Cheng, R.K.Y.,Crawley, L.,Barker, J.,Wood, M.,Felicetti, B.,Whittaker, M. (deposition date: 2009-07-10, release date: 2009-07-21, Last modification date: 2023-11-22) |
Primary citation | Cheng, R.K.Y.,Crawley, L.,Barker, J.,Wood, M.,Felicetti, B.,Whittaker, M. Crystal structure of human PDE4a with 4-(3-butoxy-4-methoxyphenyl)methyl-2-imidazolidone To be Published, |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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