3I7N

Crystal Structure of DDB1 in Complex with the H-Box Motif of WDTC1

Summary for 3I7N

• Entry DOI: 10.2210/pdb3i7n/pdb
• Related: 2B5M 3I7H 3I7K 3I7L 3I7O 3I7P 3I89 3I8C 3I8E
• Descriptor: DNA damage-binding protein 1, WD and tetratricopeptide repeats protein 1 (2 entities in total)
• Functional Keywords: ddb1, wdtc1, dcaf9, h-box motif, cytoplasm, dna damage, dna repair, dna-binding, host-virus interaction, nucleus, phosphoprotein, polymorphism, ubl conjugation, ubl conjugation pathway, alternative splicing, tpr repeat, wd repeat, protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: Q16531
• Total number of polymer chains: 2
• Total formula weight: 129058.71

Authors

Li, T.,Robert, E.I.,Breugel, P.C.V.,Strubin, M.,Zheng, N. (deposition date: 2009-07-08, release date: 2009-12-08, Last modification date: 2023-09-06)

• Primary citation: Li, T.,Robert, E.I.,van Breugel, P.C.,Strubin, M.,Zheng, N.; A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.; Nat.Struct.Mol.Biol., 17:105-111, 2010; PubMed: 19966799; DOI: 10.1038/nsmb.1719

Experimental method

X-RAY DIFFRACTION (2.8 Å)