3I54

Crystal structure of MtbCRP in complex with cAMP

3I54 の概要

• エントリーDOI: 10.2210/pdb3i54/pdb
• 関連するPDBエントリー: 3I59
• 分子名称: Transcriptional regulator, Crp/Fnr family, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total)
• 機能のキーワード: mycobacterium tuberculosis, camp receptor protein, allosteric mechanism, dna binding, inhibition, structural genomics, tb structural genomics consortium, tbsgc, dna-binding, transcription, transcription regulation, dna binding protein
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 111706.00

構造登録者

Reddy, M.C.,Palaninathan, S.K.,Bruning, J.B.,Thurman, C.,Smith, D.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (登録日: 2009-07-03, 公開日: 2009-09-08, 最終更新日: 2024-02-21)

• 主引用文献: Reddy, M.C.,Palaninathan, S.K.,Bruning, J.B.,Thurman, C.,Smith, D.,Sacchettini, J.C.; Structural Insights into the Mechanism of the Allosteric Transitions of Mycobacterium tuberculosis cAMP Receptor Protein.; J.Biol.Chem., 284:36581-36591, 2009; PubMed: 19740754; DOI: 10.1074/jbc.M109.041343

実験手法

X-RAY DIFFRACTION (2.2 Å)