3I3A

Structural Basis for the Sugar Nucleotide and Acyl Chain Selectivity of Leptospira interrogans LpxA

3I3A の概要

• エントリーDOI: 10.2210/pdb3i3a/pdb
• 関連するPDBエントリー: 3HSQ 3I3X
• 分子名称: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, S-[2-({N-[(2R)-2-hydroxy-4-{[(S)-hydroxy(methoxy)phosphoryl]oxy}-3,3-dimethylbutanoyl]-beta-alanyl}amino)ethyl] (3R)-3-hydroxydodecanethioate (3 entities in total)
• 機能のキーワード: lpxa, leptospira interrogans, leptospira interrogans complex, acyltransferase, lipid a biosynthesis, lipid synthesis, transferase
• 由来する生物種: Leptospira interrogans
• 細胞内の位置: Cytoplasm (By similarity): Q8EZA6
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 86318.29

構造登録者

Williams, A.H. (登録日: 2009-06-30, 公開日: 2009-09-01, 最終更新日: 2024-02-21)

• 主引用文献: Robins, L.I.,Williams, A.H.,Raetz, C.R.; Structural basis for the sugar nucleotide and acyl-chain selectivity of Leptospira interrogans LpxA.; Biochemistry, 48:6191-6201, 2009; PubMed: 19456129; DOI: 10.1021/bi900629e

実験手法

X-RAY DIFFRACTION (2.12 Å)