3I0L

Crystal structure of GTB C80S/C196S/C209S + DA + UDP-Gal

Summary for 3I0L

Related1LZ7 3I0C 3I0D 3I0E 3I0F 3I0G 3I0H 3I0I 3I0J 3I0K
DescriptorABO glycosyltransferase, 2-HEXYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL, ALPHA-L-FUCOSE, ... (6 entities in total)
Functional Keywordsgtb, glycosyltransferase, abo blood group, retaining, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total molecular weight34822.27
Authors
Schuman, B.,Persson, M.,Landry, R.C.,Polakowski, R.,Weadge, J.T.,Seto, N.O.L.,Borisova, S.,Palcic, M.M.,Evans, S.V. (deposition date: 2009-06-25, release date: 2010-08-11, Last modification date: 2011-07-13)
Primary citation
Schuman, B.,Persson, M.,Landry, R.C.,Polakowski, R.,Weadge, J.T.,Seto, N.O.,Borisova, S.N.,Palcic, M.M.,Evans, S.V.
Cysteine-to-serine mutants dramatically reorder the active site of human ABO(H) blood group B glycosyltransferase without affecting activity: structural insights into cooperative substrate binding
J.Mol.Biol., 402:399-411, 2010
PubMed: 20655926 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2010.07.036
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.6 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.217502.9%5.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution