3I0D

Crystal structure of GTB C80S/C196S + UDP

Summary for 3I0D

Entry DOI	10.2210/pdb3i0d/pdb
Related	1LZ7 3I0C 3I0E 3I0F 3I0G 3I0H 3I0I 3I0J 3I0K 3I0L
Descriptor	ABO glycosyltransferase, URIDINE-5'-DIPHOSPHATE (3 entities in total)
Functional Keywords	gtb, glycosyltransferase, abo blood group, retaining, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	33825.55
Authors	Schuman, B.,Persson, M.,Landry, R.C.,Polakowski, R.,Weadge, J.T.,Seto, N.O.L.,Borisova, S.,Palcic, M.M.,Evans, S.V. (deposition date: 2009-06-25, release date: 2010-08-11, Last modification date: 2023-09-06)
Primary citation	Schuman, B.,Persson, M.,Landry, R.C.,Polakowski, R.,Weadge, J.T.,Seto, N.O.,Borisova, S.N.,Palcic, M.M.,Evans, S.V. Cysteine-to-serine mutants dramatically reorder the active site of human ABO(H) blood group B glycosyltransferase without affecting activity: structural insights into cooperative substrate binding J.Mol.Biol., 402:399-411, 2010 Cited by PubMed: 20655926 DOI: 10.1016/j.jmb.2010.07.036 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation