3I0K
Crystal structure of GTB C80S/C196S/C209S + UDP + H antigen
Summary for 3I0K
Entry DOI | 10.2210/pdb3i0k/pdb |
Related | 1LZ7 3I0C 3I0D 3I0E 3I0F 3I0G 3I0H 3I0I 3I0J 3I0L |
Descriptor | ABO glycosyltransferase, alpha-L-fucopyranose-(1-2)-hexyl beta-D-galactopyranoside, URIDINE-5'-DIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | gtb, glycosyltransferase, abo blood group, retaining, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 34219.94 |
Authors | Schuman, B.,Persson, M.,Landry, R.C.,Polakowski, R.,Weadge, J.T.,Seto, N.O.L.,Borisova, S.,Palcic, M.M.,Evans, S.V. (deposition date: 2009-06-25, release date: 2010-08-11, Last modification date: 2023-09-06) |
Primary citation | Schuman, B.,Persson, M.,Landry, R.C.,Polakowski, R.,Weadge, J.T.,Seto, N.O.,Borisova, S.N.,Palcic, M.M.,Evans, S.V. Cysteine-to-serine mutants dramatically reorder the active site of human ABO(H) blood group B glycosyltransferase without affecting activity: structural insights into cooperative substrate binding J.Mol.Biol., 402:399-411, 2010 Cited by PubMed: 20655926DOI: 10.1016/j.jmb.2010.07.036 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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