3HWX

Crystal structure of menaquinone synthesis protein MenD from E. coli in complex with ThDP

Summary for 3HWX

• Entry DOI: 10.2210/pdb3hwx/pdb
• Related: 3FLM
• Descriptor: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SODIUM ION, THIAMINE DIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: menaquinone, thdp, mg, vitamin k2, carboxylase, magnesium, manganese, menaquinone biosynthesis, metal-binding, thiamine pyrophosphate, transferase
• Biological source: Escherichia coli
• Total number of polymer chains: 8
• Total formula weight: 495724.61

Authors

Priyadarshi, A.,Hwang, K.Y. (deposition date: 2009-06-19, release date: 2009-11-03, Last modification date: 2023-11-01)

• Primary citation: Priyadarshi, A.,Kim, E.E.,Hwang, K.Y.; Structural and functional analysis of Vitamin K2 synthesis protein MenD.; Biochem.Biophys.Res.Commun., 388:748-751, 2009; PubMed: 19703421; DOI: 10.1016/j.bbrc.2009.08.093

Experimental method

X-RAY DIFFRACTION (2.6 Å)