3HWX
Crystal structure of menaquinone synthesis protein MenD from E. coli in complex with ThDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, I, J, R... | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | polymer | 556 | 61449.8 | 8 | UniProt (P17109) Pfam (PF02776) Pfam (PF16582) Pfam (PF02775) In PDB | Escherichia coli | SEPHCHC synthase, Menaquinone biosynthesis protein menD |
| 2 | S, A, Z, B, 1... | SODIUM ION | non-polymer | 23.0 | 15 | Chemie (NA) | |||
| 3 | R, S, Z, A, 1... | THIAMINE DIPHOSPHATE | non-polymer | 425.3 | 8 | Chemie (TPP) | |||
| 4 | R, S, Z, A, 1... | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 5 | 1, J | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | water | water | 18.0 | 451 | Chemie (HOH) |
Sequence modifications
A, B, I, J, R, S, Z, 1: 1 - 556 (UniProt: P17109)
| PDB | External Database | Details |
|---|---|---|
| Leu 36 | Pro 36 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 491598.6 | |
| Non-Polymers* | Number of molecules | 33 |
| Total formula weight | 4126.0 | |
| All* | Total formula weight | 495724.6 |
