3HPS

Crystal structure of Mycobacterium tuberculosis LeuA complexed with ketoisocaproate (KIC)

Summary for 3HPS

• Entry DOI: 10.2210/pdb3hps/pdb
• Related: 1SR9 3FIG 3HPX 3HPZ 3HQ1
• Descriptor: 2-isopropylmalate synthase, LEUCINE, ZINC ION, ... (6 entities in total)
• Functional Keywords: 2-isopropylmalate synthase, leua, mycobacterium tuberculosis, leucine biosynthesis, enzyme, tim barrel, regulatory domain, substrate, amino-acid biosynthesis, branched-chain amino acid biosynthesis, transferase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 2
• Total formula weight: 141212.50

Authors

Koon, N.,Squire, C.J.,Baker, E.N. (deposition date: 2009-06-04, release date: 2010-05-19, Last modification date: 2023-09-06)

• Primary citation: Koon, N.,Squire, C.J.,Baker, E.N.; Probing the active site of M. tuberculosis LeuA; To be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)