3HPZ

Crystal structure of Mycobacterium tuberculosis LeuA complexed with bromopyruvate

Summary for 3HPZ

• Entry DOI: 10.2210/pdb3hpz/pdb
• Related: 1SR9 3FIG 3HPS 3HPX 3HQ1
• Descriptor: 2-isopropylmalate synthase, ZINC ION, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: 2-isopropylmalate synthase, leua, mycobacterium tuberculosis, inhibitor, inhibition, bromopyruvate, amino-acid biosynthesis, branched-chain amino acid biosynthesis, leucine biosynthesis, transferase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 2
• Total formula weight: 140927.73

Authors

Koon, N.,Squire, C.J.,Baker, E.N. (deposition date: 2009-06-05, release date: 2010-05-19, Last modification date: 2023-09-06)

• Primary citation: Koon, N.,Squire, C.J.,Baker, E.N.; Probing the active site of M. tuberculosis LeuA; To be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)