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3HPS

Crystal structure of Mycobacterium tuberculosis LeuA complexed with ketoisocaproate (KIC)

Summary for 3HPS
Entry DOI10.2210/pdb3hps/pdb
Related1SR9 3FIG 3HPX 3HPZ 3HQ1
Descriptor2-isopropylmalate synthase, LEUCINE, ZINC ION, ... (6 entities in total)
Functional Keywords2-isopropylmalate synthase, leua, mycobacterium tuberculosis, leucine biosynthesis, enzyme, tim barrel, regulatory domain, substrate, amino-acid biosynthesis, branched-chain amino acid biosynthesis, transferase
Biological sourceMycobacterium tuberculosis
Total number of polymer chains2
Total formula weight141212.50
Authors
Koon, N.,Squire, C.J.,Baker, E.N. (deposition date: 2009-06-04, release date: 2010-05-19, Last modification date: 2023-09-06)
Primary citationKoon, N.,Squire, C.J.,Baker, E.N.
Probing the active site of M. tuberculosis LeuA
To be Published,
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

217705

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