3HPS
Crystal structure of Mycobacterium tuberculosis LeuA complexed with ketoisocaproate (KIC)
Summary for 3HPS
Entry DOI | 10.2210/pdb3hps/pdb |
Related | 1SR9 3FIG 3HPX 3HPZ 3HQ1 |
Descriptor | 2-isopropylmalate synthase, LEUCINE, ZINC ION, ... (6 entities in total) |
Functional Keywords | 2-isopropylmalate synthase, leua, mycobacterium tuberculosis, leucine biosynthesis, enzyme, tim barrel, regulatory domain, substrate, amino-acid biosynthesis, branched-chain amino acid biosynthesis, transferase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 2 |
Total formula weight | 141212.50 |
Authors | Koon, N.,Squire, C.J.,Baker, E.N. (deposition date: 2009-06-04, release date: 2010-05-19, Last modification date: 2023-09-06) |
Primary citation | Koon, N.,Squire, C.J.,Baker, E.N. Probing the active site of M. tuberculosis LeuA To be Published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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