3HPL

KcsA E71H-F103A mutant in the closed state

Summary for 3HPL

Entry DOI	10.2210/pdb3hpl/pdb
Descriptor	Antibody Fab heavy chain, Antibody fab light chain, Voltage-gated potassium channel, ... (4 entities in total)
Functional Keywords	kcsa, e71h, f103a, closed, inactivation, cell membrane, ion transport, ionic channel, membrane, transmembrane, transport, voltage-gated channel, immune system-metal transport complex, immune system/metal transport
Biological source	Mus musculus (mouse) More
Cellular location	Cell membrane; Multi-pass membrane protein: P0A334
Total number of polymer chains	3
Total formula weight	60226.09
Authors	Cuello, L.G.,Jogini, V.,Cortes, D.M.,Perozo, E. (deposition date: 2009-06-04, release date: 2010-06-23, Last modification date: 2021-10-13)
Primary citation	Cuello, L.G.,Jogini, V.,Cortes, D.M.,Pan, A.C.,Gagnon, D.G.,Dalmas, O.,Cordero-Morales, J.F.,Chakrapani, S.,Roux, B.,Perozo, E. Structural basis for the coupling between activation and inactivation gates in K(+) channels. Nature, 466:272-275, 2010 Cited by PubMed: 20613845 DOI: 10.1038/nature09136 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation